Predictive Monitoring of Shake Flask Cultures with Online Estimated Growth Models

Simplicity renders shake flasks ideal for strain selection and substrate optimization in biotechnology. Uncertainty during initial experiments may, however, cause adverse growth conditions and mislead conclusions. Using growth models for online predictions of future biomass (BM) and the arrival of c...

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Bibliographic Details
Main Authors: Barbara Pretzner, Rüdiger W. Maschke, Claudia Haiderer, Gernot T. John, Christoph Herwig, Peter Sykacek
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Bioengineering
Subjects:
Online Access:https://www.mdpi.com/2306-5354/8/11/177