Loss of chromosome Y in regulatory T cells

Loss of chromosome Y in regulatory T cells

Abstract Background Mosaic loss of chromosome Y (LOY) in leukocytes is the most prevalent somatic aneuploidy in aging humans. Men with LOY have increased risks of all-cause mortality and the major causes of death, including many forms of cancer. It has been suggested that the association between LOY...

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Main Authors: Jonas Mattisson, Jonatan Halvardson, Hanna Davies, Bożena Bruhn-Olszewska, Paweł Olszewski, Marcus Danielsson, Josefin Bjurling, Amanda Lindberg, Ammar Zaghlool, Edyta Rychlicka-Buniowska, Jan P. Dumanski, Lars A. Forsberg
Format: Article
Language:English
Published: BMC 2024-03-01
Series:BMC Genomics
Subjects:
Regulatory T cells
Tregs
Mosaic loss of chromosome Y
LOY
Single-cell RNA sequencing
scRNAseq
Online Access:https://doi.org/10.1186/s12864-024-10168-7

Internet

https://doi.org/10.1186/s12864-024-10168-7

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