Methylome-wide analysis in systemic microbial-induced experimental periodontal disease in mice with different susceptibility

Methylome-wide analysis in systemic microbial-induced experimental periodontal disease in mice with different susceptibility

ObjectiveThe study delved into the epigenetic factors associated with periodontal disease in two lineages of mice, namely C57bl/6 and Balb/c. Its primary objective was to elucidate alterations in the methylome of mice with distinct genetic backgrounds following systemic microbial challenge, employin...

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Bibliographic Details
Main Authors: Cristhiam de Jesus Hernandez Martinez, Joseph Glessner, Livia Sertori Finoti, Pedro Felix Silva, Michel Messora, Ricardo Della Coletta, Hakon Hakonarson, Daniela Bazan Palioto
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-07-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
periodontal disease
methylome
DNA methylation
mouse models
Porphyromonas gingivalis
differential methylome analysis
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2024.1369226/full

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https://www.frontiersin.org/articles/10.3389/fcimb.2024.1369226/full

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