Berberine and rifaximin effects on small intestinal bacterial overgrowth: Study protocol for an investigator-initiated, double-arm, open-label, randomized clinical trial (BRIEF-SIBO study)

Berberine and rifaximin effects on small intestinal bacterial overgrowth: Study protocol for an investigator-initiated, double-arm, open-label, randomized clinical trial (BRIEF-SIBO study)

Introduction: Small intestinal bacterial overgrowth (SIBO) leads to non-specific abdominal discomfort and nutrient malabsorption. Currently, rifaximin is widely applied in SIBO based on its antibacterial and non-absorbable nature. Berberine is a natural component of many popular medicine plants that...

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Bibliographic Details
Main Authors: Huaizhu Guo, Siqi Lu, Jindong Zhang, Chen Chen, Yanlin Du, Kun Wang, Liping Duan
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Pharmacology
Subjects:
small intestinal bacteria overgrowth (SIBO)
berberine (BBR)
rifaximin
microbiota
breath test
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1121435/full

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https://www.frontiersin.org/articles/10.3389/fphar.2023.1121435/full

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