The role of mitochondrial transfer in the suppression of CD8+ T cell responses by Mesenchymal stem cells

The role of mitochondrial transfer in the suppression of CD8+ T cell responses by Mesenchymal stem cells

Abstract Background . CD8+ Cytotoxic T lymphocytes play a key role in the pathogenesis of autoimmune diseases and clinical conditions such as graft versus host disease and graft rejection. Mesenchymal Stromal Cells (MSCs) are multipotent cells with tissue repair and immunomodulatory capabilities. Si...

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Bibliographic Details
Main Authors: Loic Vaillant, Waseem Akhter, Jean Nakhle, Matthieu Simon, Martin Villalba, Christian Jorgensen, Marie-Luce Vignais, Javier Hernandez
Format: Article
Language:English
Published: BMC 2024-11-01
Series:Stem Cell Research & Therapy
Subjects:
Mesenchymal stem/stromal cells
CD8+ T cells
Mitochondrial transfer
Immunotherapy
Autoimmunity
Online Access:https://doi.org/10.1186/s13287-024-03980-1

Internet

https://doi.org/10.1186/s13287-024-03980-1

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