A role for mitochondrial oxidants in stress-induced premature senescence of human vascular smooth muscle cells

Mitochondria are a major source of cellular oxidants and have been implicated in aging and associated pathologies, notably cardiovascular diseases. Vascular cell senescence is observed in experimental and human cardiovascular pathologies. Our previous data highlighted a role for angiotensin II in th...

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Bibliographic Details
Main Authors: Yogita Mistry, Toryn Poolman, Bryan Williams, Karl E. Herbert
Format: Article
Language:English
Published: Elsevier 2013-01-01
Series:Redox Biology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231713000621