A role for mitochondrial oxidants in stress-induced premature senescence of human vascular smooth muscle cells

Mitochondria are a major source of cellular oxidants and have been implicated in aging and associated pathologies, notably cardiovascular diseases. Vascular cell senescence is observed in experimental and human cardiovascular pathologies. Our previous data highlighted a role for angiotensin II in th...

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Detalles Bibliográficos
Main Authors: Yogita Mistry, Toryn Poolman, Bryan Williams, Karl E. Herbert
Formato: Artigo
Idioma:English
Publicado: Elsevier 2013-01-01
Series:Redox Biology
Subjects:
Acceso en liña:http://www.sciencedirect.com/science/article/pii/S2213231713000621