Presynaptic 5-HT<sub>2A</sub>-mGlu2/3 Receptor–Receptor Crosstalk in the Prefrontal Cortex: Metamodulation of Glutamate Exocytosis

Presynaptic 5-HT<sub>2A</sub>-mGlu2/3 Receptor–Receptor Crosstalk in the Prefrontal Cortex: Metamodulation of Glutamate Exocytosis

The glutamatergic nerve endings of a rat prefrontal cortex (PFc) possess presynaptic 5-HT<sub>2A</sub> heteroreceptors and mGlu2/3 autoreceptors, whose activation inhibits glutamate exocytosis, and is measured as 15 mM KCl-evoked [<sup>3</sup>H]D-aspartate ([<sup>3</...

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Bibliographic Details
Main Authors:	Alice Taddeucci, Guendalina Olivero, Alessandra Roggeri, Claudio Milanese, Francesco Paolo Di Giorgio, Massimo Grilli, Mario Marchi, Beatrice Garrone, Anna Pittaluga
Format:	Article
Language:	English
Published:	MDPI AG 2022-09-01
Series:	Cells
Subjects:	synaptosomes mGlu2/3 receptor 5-HT<sub>2A</sub> receptor glutamate exocytosis trazodone prefrontal cortex
Online Access:	https://www.mdpi.com/2073-4409/11/19/3035

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