Low dose aspirin prevents endothelial dysfunction in the aorta and foetal loss in pregnant mice infected with influenza A virus

Low dose aspirin prevents endothelial dysfunction in the aorta and foetal loss in pregnant mice infected with influenza A virus

Influenza A virus (IAV) infection in pregnancy resembles a preeclamptic phenotype characterised by vascular dysfunction and foetal growth retardation. Given that low dose aspirin (ASA) is safe in pregnancy and is used to prevent preeclampsia, we investigated whether ASA or NO-conjugated aspirin, NCX...

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Bibliographic Details
Main Authors: Madison Coward-Smith, Stella Liong, Osezua Oseghale, Jonathan R. Erlich, Mark A. Miles, Felicia Liong, Kurt Brassington, Steven Bozinovski, Ross Vlahos, Robert D. Brooks, Doug A. Brooks, John J. O’Leary, Stavros Selemidis
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-04-01
Series:Frontiers in Immunology
Subjects:
pregnancy
influenza
vascular dysfunction
aspirin
foetal
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1378610/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2024.1378610/full

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