The Drosophila formin Fhos is a primary mediator of sarcomeric thin-filament array assembly

The Drosophila formin Fhos is a primary mediator of sarcomeric thin-filament array assembly

Actin-based thin filament arrays constitute a fundamental core component of muscle sarcomeres. We have used formation of the Drosophila indirect flight musculature for studying the assembly and maturation of thin-filament arrays in a skeletal muscle model system. Employing GFP-tagged actin monomer i...

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Bibliographic Details
Main Authors: Arkadi Shwartz, Nagaraju Dhanyasi, Eyal D Schejter, Ben-Zion Shilo
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2016-10-01
Series:eLife
Subjects:
muscle fiber
sarcomere
muscle actin
formin
Fhos/FHOD
Online Access:https://elifesciences.org/articles/16540

Internet

https://elifesciences.org/articles/16540

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