Mass spectrometry imaging identifies altered hepatic lipid signatures during experimental Leishmania donovani infection

Mass spectrometry imaging identifies altered hepatic lipid signatures during experimental Leishmania donovani infection

IntroductionSpatial analysis of lipids in inflammatory microenvironments is key to understand the pathogenesis of infectious disease. Granulomatous inflammation is a hallmark of leishmaniasis and changes in host and parasite lipid metabolism have been observed at the bulk tissue level in various inf...

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Bibliographic Details
Main Authors: Roel Tans, Shoumit Dey, Nidhi Sharma Dey, Jian-Hua Cao, Prasanjit S. Paul, Grant Calder, Peter O’Toole, Paul M. Kaye, Ron M. A. Heeren
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Immunology
Subjects:
leishmania
inflammation
granulomas
liver
lipids
mass spectrometry imaging
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.862104/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.862104/full

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