A RanGTP-independent mechanism allows ribosomal protein nuclear import for ribosome assembly

A RanGTP-independent mechanism allows ribosomal protein nuclear import for ribosome assembly

Within a single generation time a growing yeast cell imports ∼14 million ribosomal proteins (r-proteins) into the nucleus for ribosome production. After import, it is unclear how these intrinsically unstable and aggregation-prone proteins are targeted to the ribosome assembly site in the nucleolus....

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Bibliographic Details
Main Authors: Sabina Schütz, Ute Fischer, Martin Altvater, Purnima Nerurkar, Cohue Peña, Michaela Gerber, Yiming Chang, Stefanie Caesar, Olga T Schubert, Gabriel Schlenstedt, Vikram G Panse
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2014-08-01
Series:eLife
Subjects:
ribosome biogenesis
rRNA processing
nuclear import
Tsr2
eS26
Diamond-Blackfan anemia
Online Access:https://elifesciences.org/articles/03473

Internet

https://elifesciences.org/articles/03473

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