Adjunctive tonic motor activation enables opioid reduction for refractory restless legs syndrome: a prospective, open-label, single-arm clinical trial

Abstract Background There is a large population of restless legs syndrome (RLS) patients who are refractory to medication. Whereas experts recommend off-label opioids as an effective long-term treatment for refractory RLS, reducing opioid dose could substantially reduce side effects and risks. Tonic...

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Bibliographic Details
Main Authors: Mark J. Buchfuhrer, Asim Roy, Stephanye Rodriguez, Jonathan D. Charlesworth
Format: Article
Language:English
Published: BMC 2023-11-01
Series:BMC Neurology
Subjects:
Online Access:https://doi.org/10.1186/s12883-023-03462-6