Adjunctive tonic motor activation enables opioid reduction for refractory restless legs syndrome: a prospective, open-label, single-arm clinical trial
Abstract Background There is a large population of restless legs syndrome (RLS) patients who are refractory to medication. Whereas experts recommend off-label opioids as an effective long-term treatment for refractory RLS, reducing opioid dose could substantially reduce side effects and risks. Tonic...
Main Authors: | Mark J. Buchfuhrer, Asim Roy, Stephanye Rodriguez, Jonathan D. Charlesworth |
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Format: | Article |
Language: | English |
Published: |
BMC
2023-11-01
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Series: | BMC Neurology |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12883-023-03462-6 |
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