Comprehensive Characterization of Human Lung Large Cell Carcinoma Identifies Transcriptomic Signatures with Potential Implications in Response to Immunotherapy

Comprehensive Characterization of Human Lung Large Cell Carcinoma Identifies Transcriptomic Signatures with Potential Implications in Response to Immunotherapy

Lung cancer is the leading cause of cancer mortality worldwide, with non-small cell lung cancer (NSCLC) being the most prevalent histology. While immunotherapy with checkpoint inhibitors has shown outstanding results in NSCLC, the precise identification of responders remains a major challenge. Most...

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Bibliographic Details
Main Authors: Javier Ramos-Paradas, David Gómez-Sánchez, Aranzazu Rosado, Alvaro C. Ucero, Irene Ferrer, Ricardo García-Luján, Jon Zugazagoitia, Nuria Carrizo, Ana B. Enguita, Esther Conde, Eva M. Garrido-Martin, Luis Paz-Ares
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Journal of Clinical Medicine
Subjects:
non-small cell lung cancer
lung large cell carcinoma
immunotherapy
checkpoint inhibitors
multiparametric analysis
predictive biomarkers
Online Access:https://www.mdpi.com/2077-0383/11/6/1500

Internet

https://www.mdpi.com/2077-0383/11/6/1500

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