Distinct B cell subsets in Peyer’s patches convey probiotic effects by Limosilactobacillus reuteri

Distinct B cell subsets in Peyer’s patches convey probiotic effects by Limosilactobacillus reuteri

Abstract Background Intestinal Peyer’s patches (PPs) form unique niches for bacteria-immune cell interactions that direct host immunity and shape the microbiome. Here we investigate how peroral administration of probiotic bacterium Limosilactobacillus reuteri R2LC affects B lymphocytes and IgA induc...

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Bibliographic Details
Main Authors: Hao-Yu Liu, Antoine Giraud, Cedric Seignez, David Ahl, Feilong Guo, John Sedin, Tomas Walden, Jee-Hwan Oh, Jan Peter van Pijkeren, Lena Holm, Stefan Roos, Stefan Bertilsson, Mia Phillipson
Format: Article
Language:English
Published: BMC 2021-10-01
Series:Microbiome
Subjects:
Innate-like B lymphocytes
Inflammatory bowel disease
Gut microbiome
PD-1 dependent
Probiotics
R2LC
Online Access:https://doi.org/10.1186/s40168-021-01128-4

Internet

https://doi.org/10.1186/s40168-021-01128-4

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