Loss of DSTYK activates Wnt/β-catenin signaling and glycolysis in lung adenocarcinoma

Abstract Aberrant activation of Wnt/β-catenin signaling and dysregulation of metabolism have been frequently observed in lung cancer. However, the molecular mechanism by which Wnt/β-catenin signaling is regulated and the link between Wnt/β-catenin signaling and cancer metabolism are not fully unders...

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Bibliographic Details
Main Authors: Chenxi Zhong, Ming Chen, Yu Chen, Feng Yao, Wentao Fang
Format: Article
Language:English
Published: Nature Publishing Group 2021-12-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-021-04385-1