Nucleolar Stress Functions Upstream to Stimulate Expression of Autophagy Regulators

Ribosome biogenesis is essential for protein synthesis, cell growth and survival. The process takes places in nucleoli and is orchestrated by various proteins, among them RNA polymerases I–III as well as ribosome biogenesis factors. Perturbation of ribosome biogenesis activates the nucleolar stress...

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Bibliographic Details
Main Authors: David P. Dannheisig, Anna Schimansky, Cornelia Donow, Astrid S. Pfister
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/13/24/6220