Activation and pro-inflammatory cytokine production by unswitched memory B cells during SARS-CoV-2 infection

Activation and pro-inflammatory cytokine production by unswitched memory B cells during SARS-CoV-2 infection

Memory B cells are comprised of unswitched (CD27+IgD+) and switched (CD27+IgD-) subsets. The origin and function of unswitched human memory B cells are debated in the literature, whereas switched memory B cells are primed to respond to recurrent infection. Unswitched memory B cells have been describ...

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Bibliographic Details
Main Authors: Moriah J. Castleman, Adriana Luna Santos, Kelsey E. Lesteberg, James P. Maloney, William J. Janssen, Kara J. Mould, J. David Beckham, Roberta Pelanda, Raul M. Torres
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-08-01
Series:Frontiers in Immunology
Subjects:
unswitched memory
switched memory
B cells
COVID - 19
SARS-CoV- 2
human
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1213344/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2023.1213344/full

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