Activation and pro-inflammatory cytokine production by unswitched memory B cells during SARS-CoV-2 infection
Memory B cells are comprised of unswitched (CD27+IgD+) and switched (CD27+IgD-) subsets. The origin and function of unswitched human memory B cells are debated in the literature, whereas switched memory B cells are primed to respond to recurrent infection. Unswitched memory B cells have been describ...
Main Authors: | Moriah J. Castleman, Adriana Luna Santos, Kelsey E. Lesteberg, James P. Maloney, William J. Janssen, Kara J. Mould, J. David Beckham, Roberta Pelanda, Raul M. Torres |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2023-08-01
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Series: | Frontiers in Immunology |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fimmu.2023.1213344/full |
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