Bone Marrow Microenvironment-On-Chip for Culture of Functional Hematopoietic Stem Cells

Hematopoiesis takes place in the bone marrow and is supported by a complex cellular and molecular network in the bone marrow microenvironment. Commonly used models of the human bone marrow microenvironment include murine models and two-dimensional and three-dimensional tissue cultures. While these m...

Full description

Bibliographic Details
Main Authors: Azmeer Sharipol, Maggie L. Lesch, Celia A. Soto, Benjamin J. Frisch
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2022.855777/full