Synthesis of N-phenyl- and N-thiazolyl-1H-indazoles by copper-catalyzed intramolecular N-arylation of ortho-chlorinated arylhydrazones

Synthesis of N-phenyl- and N-thiazolyl-1H-indazoles by copper-catalyzed intramolecular N-arylation of ortho-chlorinated arylhydrazones

The broad application of 1H-indazoles has prompted the development of several approaches for the synthesis of such compounds, including metal-free, palladium-, or copper-promoted intramolecular N-arylation of in situ-generated or isolated o-haloarylhydrazones. Such methods mainly start from o-bromo...

Full description

Bibliographic Details
Main Authors: Yara Cristina Marchioro Barbosa, Guilherme Caneppele Paveglio, Claudio Martin Pereira de Pereira, Sidnei Moura, Cristiane Storck Schwalm, Gleison Antonio Casagrande, Lucas Pizzuti
Format: Article
Language:English
Published: Beilstein-Institut 2022-08-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
fused-ring systems
hydrazones
indazoles
intramolecular cyclization
n-heterocycles
Online Access:https://doi.org/10.3762/bjoc.18.110

Internet

https://doi.org/10.3762/bjoc.18.110

Similar Items