PI3K mutations in breast cancer: prognostic and therapeutic implications
Toru MukoharaCancer Center and Division of Medical Oncology/Hematology, Kobe University Hospital, Kobe, JapanAbstract: The PI3K pathway is the most frequently enhanced oncogenic pathway in breast cancer. Among mechanisms of PI3K enhancement, PIK3CA mutations are most frequently (~30%) observed, alon...
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| Format: | Article |
| Language: | English |
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Dove Medical Press
2015-05-01
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| Series: | Breast Cancer: Targets and Therapy |
| Online Access: | http://www.dovepress.com/pi3k-mutations-in-breast-cancer-prognostic-and-therapeutic-implication-peer-reviewed-article-BCTT |