oprC Impairs Host Defense by Increasing the Quorum-Sensing-Mediated Virulence of Pseudomonas aeruginosa

oprC Impairs Host Defense by Increasing the Quorum-Sensing-Mediated Virulence of Pseudomonas aeruginosa

Pseudomonas aeruginosa, found widely in the wild, causes infections in the lungs and several other organs in healthy people but more often in immunocompromised individuals. P. aeruginosa infection leads to inflammasome assembly, pyroptosis, and cytokine release in the host. OprC is one of the bacter...

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Bibliographic Details
Main Authors: Pan Gao, Kai Guo, Qinqin Pu, Zhihan Wang, Ping Lin, Shugang Qin, Nadeem Khan, Junguk Hur, Haihua Liang, Min Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Immunology
Subjects:
Pseudomonas aeruginosa
oprC
virulence
pyroptosis
STAT3/NF-κB
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.01696/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.01696/full

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