Expression of Proteolytic Enzymes by Small Cell Lung Cancer Circulating Tumor Cell Lines

Expression of Proteolytic Enzymes by Small Cell Lung Cancer Circulating Tumor Cell Lines

Small cell lung cancer (SCLC) is an aggressive type of lung cancer which disseminates vigorously and has a dismal prognosis. Metastasis of SCLC is linked to an extremely high number of circulating tumor cells (CTCs), which form chemoresistant spheroids, termed tumorospheres. Intravasation and extrav...

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Bibliographic Details
Main Authors: Barbara Rath, Lukas Klameth, Adelina Plangger, Maximilian Hochmair, Ernst Ulsperger, Ihor Huk, Robert Zeillinger, Gerhard Hamilton
Format: Article
Language:English
Published: MDPI AG 2019-01-01
Series:Cancers
Subjects:
small cell lung cancer
circulating tumor cells
proteases
MMP-9
cathepsin S
metastasis
Online Access:http://www.mdpi.com/2072-6694/11/1/114

Internet

http://www.mdpi.com/2072-6694/11/1/114

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