COVID-19 and the potential of Janus family kinase (JAK) pathway inhibition: A novel treatment strategy

COVID-19 and the potential of Janus family kinase (JAK) pathway inhibition: A novel treatment strategy

Recent evidence proposed that the severity of the coronavirus disease 2019 (COVID-19) in patients is a consequence of cytokine storm, characterized by increased IL-1β, IL-6, IL-18, TNF-α, and IFN-γ. Hence, managing the cytokine storm by drugs has been suggested for the treatment of patients with sev...

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Bibliographic Details
Main Authors: Mansoor Khaledi, Fatemeh Sameni, Sheida Yahyazade, Maedeh Radandish, Parviz Owlia, Nader Bagheri, Hamed Afkhami, Mohamad Mahjoor, Zahra Esmaelpour, Maryam Kohansal, Farzad Aghaei
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Medicine
Subjects:
COVID-19
JAK inhibitors
baricitinib
pacritinib
ruxolitinib
tofacitinib
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2022.961027/full

Internet

https://www.frontiersin.org/articles/10.3389/fmed.2022.961027/full

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