Transcriptome analysis of human cholangiocytes exposed to carcinogenic 1,2-dichloropropane in the presence of macrophages in vitro

Transcriptome analysis of human cholangiocytes exposed to carcinogenic 1,2-dichloropropane in the presence of macrophages in vitro

Abstract 1,2-Dichloropropane (1,2-DCP), a synthetic organic solvent, has been implicated in causality of cholangiocarcinoma (bile duct cancer). 1,2-DCP-induced occupational cholangiocarcinoma show a different carcinogenic process compared to common cholangiocarcinoma, but its mechanism remains elusi...

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Bibliographic Details
Main Authors: Abigail Ekuban, Shigeyuki Shichino, Cai Zong, Frederick Adams Ekuban, Kazuo Kinoshita, Sahoko Ichihara, Kouji Matsushima, Gaku Ichihara
Format: Article
Language:English
Published: Nature Portfolio 2022-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-15295-3

Internet

https://doi.org/10.1038/s41598-022-15295-3

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