Analysis of the susceptibility of refractory hepatitis C virus resistant to nonstructural 5A inhibitors

Analysis of the susceptibility of refractory hepatitis C virus resistant to nonstructural 5A inhibitors

Abstract Resistance-associated substitutions (RASs) of hepatitis C virus (HCV) affect the efficacy of direct-acting antivirals (DAAs). In this study, we aimed to clarify the susceptibility of the coexistence of nonstructural (NS) 5A Q24K/L28M/R30Q (or R30E)/A92K RASs, which were observed in patients...

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Bibliographic Details
Main Authors: Ai Toyodome, Seiichi Mawatari, Hiromi Eguchi, Midori Takeda, Kotaro Kumagai, Ohki Taniyama, Sho Ijuin, Haruka Sakae, Kazuaki Tabu, Kohei Oda, Masanori Ikeda, Akio Ido
Format: Article
Language:English
Published: Nature Portfolio 2024-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-024-67169-5

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https://doi.org/10.1038/s41598-024-67169-5

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