Dihydromyricetin promotes LDL metabolism in HepG2 cells through the PCSK9/LDLR pathway

Dihydromyricetin promotes LDL metabolism in HepG2 cells through the PCSK9/LDLR pathway

ABSTRACTLow-density lipoprotein receptor (LDLR) and proprotein convertase subtilisin/kexin type 9 (PCSK9) play a pivotal role by regulating plasma low-density lipoprotein cholesterol (LDL-c) levels. Dihydromyricetin (DMY), the most abundant natural flavonoid in rattan tea, has proven anti-atherogeni...

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Bibliographic Details
Main Authors: Li-Tian Wang, Dan-Dan Hu, Hua-Rong Liu, Huai-Liu Yin, Rui Mu, Yu-Hang Yang, Run-Yu Zhao, Jun Sheng, Ye-Wei Huang, Xuan-Jun Wang
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:CyTA - Journal of Food
Subjects:
Cholesterol metabolism
ASCVD
HNF1A
LDLR
PCSK9
Online Access:https://www.tandfonline.com/doi/10.1080/19476337.2023.2252044

Internet

https://www.tandfonline.com/doi/10.1080/19476337.2023.2252044

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