RecJ3/4-aRNase J form a Ubl-associated nuclease complex functioning in survival against DNA damage in Haloferax volcanii

RecJ3/4-aRNase J form a Ubl-associated nuclease complex functioning in survival against DNA damage in Haloferax volcanii

ABSTRACT Nucleases are strictly regulated and often localized in the cell to avoid the uncontrolled degradation of DNA and RNA. Here, a new type of nuclease complex, composed of RecJ3, RecJ4, and aRNase J, was identified through its ATP-dependent association with the ubiquitin-like SAMP1 and AAA-ATP...

Full description

Bibliographic Details
Main Authors: Huiyong Jia, Swathi Dantuluri, Shae Margulies, Victoria Smith, Rebecca Lever, Thorsten Allers, Jin Koh, Sixue Chen, Julie A. Maupin-Furlow
Format: Article
Language:English
Published: American Society for Microbiology 2023-08-01
Series:mBio
Subjects:
post-translational modification
ubiquitin
proteasomes
DNA repair
archaea
Online Access:https://journals.asm.org/doi/10.1128/mbio.00852-23

Internet

https://journals.asm.org/doi/10.1128/mbio.00852-23

Similar Items