Characteristic of Perineural Invasion in Hilar Cholangiocarcinoma Based on Whole-Mount Histologic Large Sections of Liver

Characteristic of Perineural Invasion in Hilar Cholangiocarcinoma Based on Whole-Mount Histologic Large Sections of Liver

Background & ObjectivePerineural invasion is an important biological feature of hilar cholangiocarcinoma (HCCA). We developed a whole-mount histologic large sections (WHLS) of the liver to evaluate peripheral nerve invasion (PNI) of HCCA.MethodsUsing sampling, fixation, dehydration, embeddin...

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Bibliographic Details
Main Authors: Si-Yuan Wang, Nan Jiang, Jian-Ping Zeng, Shao-Qing Yu, Ying Xiao, Shuo Jin
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-03-01
Series:Frontiers in Oncology
Subjects:
panoramic immunohistochemistry
whole-mount histologic large sections
tumor biological behavior
pathological digital imaging
pathological methodology
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.855615/full

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https://www.frontiersin.org/articles/10.3389/fonc.2022.855615/full

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