Toxin expression during Staphylococcus aureus infection imprints host immunity to inhibit vaccine efficacy
Abstract Staphylococcus aureus infections are a major public health issue, and a vaccine is urgently needed. Despite a considerable promise in preclinical models, all vaccines tested thus far have failed to protect humans against S. aureus. Unlike laboratory mice, humans are exposed to S. aureus thr...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2023-01-01
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| Series: | npj Vaccines |
| Online Access: | https://doi.org/10.1038/s41541-022-00598-3 |