Anomalous Scaling of Gene Expression in Confined Cell-Free Reactions
Abstract Cellular surface breaks the symmetry of molecular diffusion across membrane. Here, we study how steric interactions between the surface and the bulk of cell-sized emulsion droplets alters gene expression emulated by a cell-free transcription/translation (TXTL) system. The concentration of s...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2018-05-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-018-25532-3 |