The Rip1 intramembrane protease contributes to iron and zinc homeostasis in Mycobacterium tuberculosis

The Rip1 intramembrane protease contributes to iron and zinc homeostasis in Mycobacterium tuberculosis

ABSTRACT Mycobacterium tuberculosis is exposed to a variety of stresses during a chronic infection, as the immune system simultaneously produces bactericidal compounds and starves the pathogen of essential nutrients. The intramembrane protease, Rip1, plays an important role in the adaptation to thes...

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Bibliographic Details
Main Authors: Samantha J. Nelson, John T. Williams, John A. Buglino, Subhalaxmi Nambi, Lisa J. Lojek, Michael S. Glickman, Thomas R. Ioerger, Christopher M. Sassetti
Format: Article
Language:English
Published: American Society for Microbiology 2023-08-01
Series:mSphere
Subjects:
iron homeostasis
nutritional immunity
Mycobacterium tuberculosis
zinc
sigma factors
Online Access:https://journals.asm.org/doi/10.1128/msphere.00389-22

Internet

https://journals.asm.org/doi/10.1128/msphere.00389-22

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