Variations in HBA gene contribute to high-altitude hypoxia adaptation via affected O2 transfer in Tibetan sheep

Variations in HBA gene contribute to high-altitude hypoxia adaptation via affected O2 transfer in Tibetan sheep

Abstract Tibetan sheep are indigenous to the Qinghai-Xizang Plateau. Owing to the harsh hypoxic environment in this plateau, the hemoglobin (Hb) protein in Tibetan sheep has undergone adaptive changes over time. Hb is primarily responsible for transporting O2 and CO2 between the lungs and other tiss...

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Bibliographic Details
Main Authors: Pengfei Zhao, Xiong Ma, Jianming Ren, Lan Zhang, Yunxin Min, Chunyang Li, Yaoyao Lu, Ying Ma, Mingjie Hou, Hui Jia
Format: Article
Language:English
Published: BMC 2024-11-01
Series:Frontiers in Zoology
Subjects:
Tibetan sheep
HBA
Hypoxia adaptation
Online Access:https://doi.org/10.1186/s12983-024-00551-1

Internet

https://doi.org/10.1186/s12983-024-00551-1

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