The spatial distribution of LGR5+ cells correlates with gastric cancer progression.

In this study we tested the prevalence, histoanatomical distribution and tumour biological significance of the Wnt target protein and cancer stem cell marker LGR5 in tumours of the human gastrointestinal tract. Differential expression of LGR5 was studied on transcriptional (real-time polymerase chai...

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Bibliographic Details
Main Authors: Eva Simon, Diana Petke, Christine Böger, Hans-Michael Behrens, Viktoria Warneke, Matthias Ebert, Christoph Röcken
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22530031/pdf/?tool=EBI