Encapsulation of a drug into electrospun fibers spun from water soluble polymers to control solubility and release
Electrospun fibers prepared from water-soluble polymers (PVP, PVA, and HPMC) were loaded with pregabalin, a BCS I drug, to address its fast release and adverse effects. The drug dissolved partially (1.8–2.8 wt%) in the polymers, with excess pregabalin in crystalline form within the fibers. The solub...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2024-10-01
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| Series: | Heliyon |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2405844024149663 |