Rhein Improves Renal Fibrosis by Restoring Cpt1a-Mediated Fatty Acid Oxidation through SirT1/STAT3/twist1 Pathway

The latest progress in the field of renal fibrosis mainly focuses on the new concept of “partial epithelial-mesenchymal transition (pEMT)” to explain the contribution of renal tubular epithelial (RTE) cells to renal fibrosis and the crucial role of fatty acid oxidation (FAO) dysfunction in RTE cells...

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Bibliographic Details
Main Authors: Xianrui Song, Zesen Du, Zhenqi Yao, Xiaoyan Tang, Mian Zhang
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/27/7/2344