PACAP attenuates hepatic lipid accumulation through the FAIM/AMPK/IRβ axis during overnutrition

PACAP attenuates hepatic lipid accumulation through the FAIM/AMPK/IRβ axis during overnutrition

Objective: Pituitary adenylate cyclase-activating polypeptide (PACAP) was reported to attenuate hepatic lipid accumulation in overnutrition-related metabolic disorder, mediated by up-regulation of fas apoptosis inhibitory molecule (FAIM). However, how PACAP regulates FAIM in metabolic tissues remain...

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Bibliographic Details
Main Authors: Wei Luo, Jiaxin Dai, Jianmin Liu, Yongmei Huang, Ziqiong Zheng, Pei Xu, Yi Ma
Format: Article
Language:English
Published: Elsevier 2022-11-01
Series:Molecular Metabolism
Subjects:
AMPK
FAIM
IRβ
PACAP
Hepatic lipid accumulation
Lipogenesis
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877822001533

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http://www.sciencedirect.com/science/article/pii/S2212877822001533

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