A novel TCF7L2 type 2 diabetes SNP identified from fine mapping in African American women.

SNP rs7903146 in the Wnt pathway's TCF7L2 gene is the variant most significantly associated with type 2 diabetes to date, with associations observed across diverse populations. We sought to determine whether variants in other Wnt pathway genes are also associated with this disease. We evaluated...

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Bibliographic Details
Main Authors: Stephen A Haddad, Julie R Palmer, Kathryn L Lunetta, Maggie C Y Ng, MEDIA Consortium, Edward A Ruiz-Narváez
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5333820?pdf=render