Discovery of a synthetic taiwaniaquinoid with potent in vitro and in vivo antitumor activity against breast cancer cells

Discovery of a synthetic taiwaniaquinoid with potent in vitro and in vivo antitumor activity against breast cancer cells

Taiwaniaquinoids are a unique family of diterpenoids predominantly isolated from Taiwania cryptomerioides Hayata. Previously, we evaluated the antiproliferative effect of several synthetic taiwaniaquinoids against human lung (A-549), colon (T-84), and breast (MCF-7) tumor cell lines. Herein, we repo...

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Bibliographic Details
Main Authors: Nuria Mut-Salud, Juan J. Guardia, Antonio Fernández, Isabel Blancas, Houda Zentar, José M. Garrido, Enrique Álvarez-Manzaneda, Rachid Chahboun, Fernando Rodríguez-Serrano
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Taiwaniaquinoids
Cancer
Apoptosis
Cell cycle arrest
Oxidative stress
In vivo
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332223015895

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http://www.sciencedirect.com/science/article/pii/S0753332223015895

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