Metabolism of homologous and heterologous lipoproteins by cultured rat and human skin fibroblasts1

Rat fibroblasts degraded human low density lipoprotein (LDL) very slowly, one-tenth to one-fortieth the rates observed in human fibroblasts. In rat cells, human LDL caused only very small increases in cell cholesterol content and acylCoA:cholesterol acyltransferase (ACAT) activity and caused only sm...

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Bibliographic Details
Main Authors: C A Drevon, A D Attie, S H Pangburn, D Steinberg
Format: Article
Language:English
Published: Elsevier 1981-01-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520347386