Metabolism of homologous and heterologous lipoproteins by cultured rat and human skin fibroblasts1

Metabolism of homologous and heterologous lipoproteins by cultured rat and human skin fibroblasts1

Rat fibroblasts degraded human low density lipoprotein (LDL) very slowly, one-tenth to one-fortieth the rates observed in human fibroblasts. In rat cells, human LDL caused only very small increases in cell cholesterol content and acylCoA:cholesterol acyltransferase (ACAT) activity and caused only sm...

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Bibliographic Details
Main Authors:	C A Drevon, A D Attie, S H Pangburn, D Steinberg
Format:	Article
Language:	English
Published:	Elsevier 1981-01-01
Series:	Journal of Lipid Research
Subjects:	cholesterol β-hydroxy-β-methylglutaryl CoA reductase acy1CoA:cholesterol acyltransferase 25-hydroxycholesterol low density lipoprotein high density lipoprotein
Online Access:	http://www.sciencedirect.com/science/article/pii/S0022227520347386

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