Altered functional responses by PAR1 agonist in murine dextran sodium sulphate-treated colon
Abstract Protease-activated receptor-1 (PAR1) is highly expressed in murine colonic smooth muscles. Responses to PAR1 activation are complex and result from responses in multiple cell types. We investigated whether PAR1 responses are altered in inflamed colon induced by dextran sodium sulfate (DSS)-...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2022-10-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-022-21285-2 |