SARS-CoV-2 S1 Subunit Booster Vaccination Elicits Robust Humoral Immune Responses in Aged Mice

SARS-CoV-2 S1 Subunit Booster Vaccination Elicits Robust Humoral Immune Responses in Aged Mice

ABSTRACT The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants has raised concerns about reduced vaccine effectiveness and the increased risk of infection, and while repeated homologous booster shots are recommended for elderly and immunocompromised individuals, they...

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Bibliographic Details
Main Authors: Eun Kim, Muhammad S. Khan, Alessandro Ferrari, Shaohua Huang, Josè C. Sammartino, Elena Percivalle, Thomas W. Kenniston, Irene Cassaniti, Fausto Baldanti, Andrea Gambotto
Format: Article
Language:English
Published: American Society for Microbiology 2023-06-01
Series:Microbiology Spectrum
Subjects:
COVID-19
SARS-CoV-2
S1 recombinant protein
adenovirus-vectored vaccine
subunit vaccine
prime-boost
Online Access:https://journals.asm.org/doi/10.1128/spectrum.04363-22

Internet

https://journals.asm.org/doi/10.1128/spectrum.04363-22

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