Bicarbonate Transport in Cystic Fibrosis and Pancreatitis

CFTR, the cystic fibrosis (CF) gene-encoded epithelial anion channel, has a prominent role in driving chloride, bicarbonate and fluid secretion in the ductal cells of the exocrine pancreas. Whereas severe mutations in <i>CFTR</i> cause fibrosis of the pancreas in utero, CFTR mutants with...

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Bibliographic Details
Main Authors: Dora Angyal, Marcel J. C. Bijvelds, Marco J. Bruno, Maikel P. Peppelenbosch, Hugo R. de Jonge
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/11/1/54