CTLA-4 gene mutation and multiple sclerosis: A case report and literature review

CTLA-4 gene mutation and multiple sclerosis: A case report and literature review

We reported a patient with autoimmunity (multiple sclerosis), immunodeficiency (hypogammaglobulinemia with severe infections), enteropathy (diarrhea with intestinal inflammation), splenomegaly, lymphadenopathy and lymphocytic infiltration of non-lymphoid organs (lung, gut and brain). The patient was...

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Bibliographic Details
Main Authors: Ting-Wei Lin, Ya-Chiao Hu, Yao-Hsu Yang, Yin-Hsiu Chien, Ni-Chung Lee, Hsin-Hui Yu, Bor-Luen Chiang, Li-Chieh Wang
Format: Article
Language:English
Published: Elsevier 2022-06-01
Series:Journal of Microbiology, Immunology and Infection
Subjects:
Abatacept
Cytotoxic T lymphocyte antigen-4
Multiple sclerosis
Primary immunodeficiency
Online Access:http://www.sciencedirect.com/science/article/pii/S168411822100236X

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http://www.sciencedirect.com/science/article/pii/S168411822100236X

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