Bayesian inference of metabolic kinetics from genome-scale multiomics data.

Modern biological tools generate a wealth of data on metabolite and protein concentrations that can be used to help inform new strain designs. However, learning from these data to predict how a cell will respond to genetic changes, a key need for engineering, remains challenging. A promising techniq...

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Bibliographic Details
Main Authors: Peter C St John, Jonathan Strutz, Linda J Broadbelt, Keith E J Tyo, Yannick J Bomble
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-11-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1007424