Bayesian inference of metabolic kinetics from genome-scale multiomics data.
Modern biological tools generate a wealth of data on metabolite and protein concentrations that can be used to help inform new strain designs. However, learning from these data to predict how a cell will respond to genetic changes, a key need for engineering, remains challenging. A promising techniq...
Main Authors: | Peter C St John, Jonathan Strutz, Linda J Broadbelt, Keith E J Tyo, Yannick J Bomble |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2019-11-01
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Series: | PLoS Computational Biology |
Online Access: | https://doi.org/10.1371/journal.pcbi.1007424 |
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