Lessons from model organisms: phenotypic robustness and missing heritability in complex disease.

Genetically tractable model organisms from phages to mice have taught us invaluable lessons about fundamental biological processes and disease-causing mutations. Owing to technological and computational advances, human biology and the causes of human diseases have become accessible as never before....

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Bibliographic Details
Main Authors: Christine Queitsch, Keisha D Carlson, Santhosh Girirajan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3499356?pdf=render